Why CBD Helps You Get Off Pharmaceuticals

If you’ve done any research into CBD, you’ve likely heard it touted as a miracle compound with uses in medical applications ranging from chronic pain to epilepsy to even cancer.  While we’re firm believers in the necessity of further scientific research on CBD and other cannabinoids, preliminary studies, combined with the stories of thousands of patients, are compelling—CBD has been known for decades to be a potent antioxidant (a compound with cancer-fighting properties), and recent research has shown it to effectively treat a variety of symptoms.

The reason CBD is so effective against so many conditions is its anti-inflammatory action. Think about it: inflammation is the root of a variety of conditions, from type II diabetes to heart disease to epilepsy, and treating that inflammation can help alleviate symptoms. CBD also has analgesic (pain-relieving) and anxiolytic (anti-anxiety) properties, broadening its potential applications to cover a wide variety of illnesses. This is all great news, as it means that it is possible to replace your pharmaceutical regimen with CBD!

That said, CBD has another added benefit that is less well-known: it helps stave off the symptoms of medication withdrawal. This makes it an especially good choice for those seeking to get off the pharmaceutical roller coaster, as it can help ease the transition when discontinuing your medications. Today, we want to discuss the science of how CBD alleviates withdrawal symptoms, and how you can use it to get yourself off of pharmaceuticals, many of which carry the potential to cause undesirable side effects, including addiction and dependence.

How CBD Acts On the Body

CBD works naturally with your endocannabinoid system, which is a system of two different types of receptors (called CB1 and CB2, though scientists suspect there may be one or more other types that have yet to be discovered. There are also other cannabinoid receptors that do not bind to THC (which we’ll discuss in more detail in a moment) working together to help regulate your body and maintain homeostasis. A term originating from the Greek homio meaning “stable” or “equal,” homeostasis refers to the stable, natural condition of your body in a relaxed state. CBD helps stimulate the endocannabinoid system to support this state, bringing your body closer to homeostasis and soothing a variety of bodily systems.

The Science of CBD at a Molecular Level

CBD is interesting in that it doesn’t directly act on either the CB1 or CB2 receptor. Instead, it acts on a variety of other cannabinoid receptors like TRPV-1, adenosine, and serotonin receptors to regulate the systems of the body. This sounds complex, but we’ll explain what each of these actions mean in practice.

The TRPV-1 receptor regulates things like body temperature, pain perception, and inflammation, and is responsible for many of the primary effects of CBD. CBD binds to this receptor like a lock to a key, stimulating it and helping regulate these symptoms.

CBD’s action on adenosine receptors is especially interesting: not only does its action on the receptor help reduce both anxiety and inflammation, but the adenosine receptor itself is involved in the production of glutamate and dopamine. Dopamine is a familiar compound that is involved in motor control, cognition, and motivation, while glutamate mediates excitatory signals and is involved in memory, learning, and cognition.

Now, directly to our point: CBD acts on serotonin receptors—specifically the 5-HT1A serotonin receptor, which is involved in a variety of systems, including pain perception, nausea, appetite, anxiety, sleep and, most importantly for today’s purposes, addiction circuits.  Stimulation of this receptor can help alleviate some of the physical symptoms of withdrawal, as well as soothing the neurons involved in the addiction pathway created by many pharmaceuticals.

Using CBD to Help Get Off Pharmaceuticals

Studies so far have shown that it takes a fairly high dose of CBD to stimulate the 5-HT1A receptor, so you may need to take a higher dose while you’re tapering than you might otherwise in order to keep withdrawals at bay. That’s okay! Unlike pharmaceuticals, CBD doesn’t require you to wean yourself off, so you can always decrease your dose when you’re out of the withdrawal period.

While CBD can work nearly instantaneously depending on the method you use to take it, it is most effective when used over time. This is why we recommend starting your CBD regimen and finding a comfortable dose, then maintaining that for at least two weeks before you begin your chosen tapering program. This will allow the CBD to act as a preventive for withdrawals while also giving you the flexibility to adjust your dose if necessary.

A Quick Note About Types of Withdrawal

Before we close, we need to discuss the nature of withdrawal symptoms, the types of withdrawal periods, and how to adjust your tapering schedule if you feel withdrawal symptoms coming on. First, you need to know what to expect from discontinuing your particular medication: some withdrawal symptoms, like those from opioids, are fairly well-known, while others, like the “brain zaps” associated with withdrawal from some antidepressants, are less well-understood and can be very disconcerting if you don’t know what they are. Furthermore, some medications, particularly psychotropics, have a notoriously long withdrawal period, and riding it out may not be feasible or healthy.

While increasing your dose of CBD can be helpful in treating your symptoms, don’t rule out temporarily restoring your pharmaceutical dose before trying tapering again, this time at a lower increment. Tapering safely may not be a perfectly linear process, and that’s okay! Try using CBD to help ease your withdrawal symptoms, but don’t get discouraged if it doesn’t work for you or your withdrawals are too severe and you have to temporarily restore your dose. It doesn’t make you weak or less determined to discontinue these medications, and eventually you will succeed. Listen to your body and treat yourself with kindness during this time, and the rest will come. We’ve written a comprehensive CBD eBook designed to make this process even easier for you!

A Note on Drug Testing

Much of the data we have about CBD is anecdotal, and its potential impact on drug testing is no exception.  There are very few peer-reviewed studies on the subject, and the ones available paint a rather murky picture:  avoiding full-spectrum products containing traces of THC can reduce your risk of a false positive, but that may not eliminate the risk entirely.  A single study (as yet unconfirmed) suggests that even isolate-based products may not be completely risk-free under certain circumstances.

If you are concerned about passing a drug test, you’ll need to consider this potential risk when deciding whether CBD is right for you. To learn more about the science of CBD and drug testing, check out our article for a more thorough discussion of how to minimize your risk of a false positive.

Conclusion

CBD can treat withdrawal symptoms at a variety of levels by acting on multiple different cannabinoid receptors, alleviating not just the physical symptoms of withdrawal but also soothing the circuits underlying addiction. Since it carries no potential for abuse, addiction, or overdose and can be applied to a vast array of medical conditions, CBD is a viable and attractive option for many patients looking to abandon the pharmaceutical carousel.

How to use CBD vs Painkillers: 50% of People Say CBD Works Better

 

One of the most amazing things about the cannabis plant is the breadth of ailments it’s capable of alleviating. Patients who have used painkillers for years have started to take notice, and researchers were curious about the effectiveness of the switch. In an August study, market-research firm Brightfield Group surveyed 2,400 registered users of Hello MD and found that 42 percent of people who use CBD report that they’ve given up pharmaceutical drugs and replaced them with some form of cannabis.

We note that this figure includes all types of cannabis, ranging from high-THC medicinal marijuana with strong CBD content to CBD-only wellness products. Most importantly, 52 percent of respondents agreed that CBD is “more effective,” or “much more effective” than pharmaceutical drugs. The important thing to realize is that while THC is the compound that provides the psychoactive properties, all THC strains will contain CBD to some degree (it’s the 2nd most prevalent cannabinoid after THC). The results are clear, those 52% of respondents were blown away by CBD’s pain management properties.

Why is CBD More Effective

Instead of introducing a foreign substance to the body that may disrupt other functions and complicate things with side effects, try CBD. Why? Because the compounds in CBD are naturally occurring in your body already. Therefore, CBD works seamlessly with your body, it knows how to make you healthier in tandem with your immune system. Using CBD on a daily basis is no different than taking a daily vitamin with essentials compounds that your body needs.

How to Switch Effectively

Pace yourself, on both the decrease and the increase. The problem with switching from painkillers to from medical marijuana or high-CBD medicine is that it’s easy to swap “one addiction for another”. We’re not saying cannabis is addictive (it’s not) but we are suggesting that it can be difficult to switch from the numbness delivered by the painkillers to that peacefulness provided by cannabis.

The goal is to be able to get off the couch, and move beyond the non-functional opioid-induced state. It’s absolutely possible to operate normally on cannabis, and especially CBD-rich products because they do not get you ‘high’ in the traditional, psychoactive sense.

We always recommend starting slowly with the dosage (5-10mg to start), trying different ingestion methods and/or incorporating light exercise like walking, yoga, swimming or biking. Activity gets the blood pumping, which will help your body circulate the beneficial compounds more effectively than if you remained sedentary. CBD is phenomenal for recovery after exercise as well because it naturally works to ease pain and soothe sore muscles, ligaments and joints.

How to Use CBD Responsibly

If you manage your dosage at first and try different products to find the best one for you, there is no reason why you can’t live a normal life with a daily CBD regimen. Between smoking, vaping, topicals, tinctures, and salves, there is a great product out there for you.

While you won’t feel high like typical cannabis, you will certainly notice the “wave of relief” that most people describe in relation to the onset of CBD. You can also view our full CBD for pain management guide for more in-depth daily regimen advice.

A Quick Note About CBD & Drug Testing

If drug testing is a part of the conditions of your employment, you might be concerned about the potential of CBD to cause you to test positive for THC. This isn’t an unfounded concern — however, there isn’t exactly a cut-and-dry way to answer it.

Much of the data we have about CBD is anecdotal, and its potential impact on drug testing is no exception.  There are very few peer-reviewed studies on the subject, but there appears to be a small risk of a false positive for some users. Avoiding full-spectrum products containing traces of THC can reduce your risk of a false positive, but that may not eliminate the risk entirely.

If you are concerned about passing a drug test, you should consider this potential risk when deciding whether CBD is right for you. To learn more about the science of CBD and drug testing, check out our article for a more thorough discussion of how to minimize your risk of a false positive.